Martine Rothblatt – Net worth: $600 million

Martine Rothblatt first found major success in 1990 with the founding of Sirius Satellite Radio. After her daughter was diagnosed with a life-threatening illness, she shifted her focus toward biotechnology.
She went on to establish United Therapeutics, which continues to operate at the forefront of medical innovation and has contributed to Rothblatt building a fortune of around $600 million.